Digoxin 5 Terms of Use Diarrhea is another side effect of consuming aloe vera juice. However, a review published in the Journal of Environmental Science and Health in January 2019 reported that aloe vera whole leaf extract showed evidence of carcinogenic activity in animals and was classified as a possible human carcinogen. Now retired, Gord enjoys a quiet life on a small island in the Gulf Islands of B.C. Speak with your doctor if you intend to drink aloe vera juice and take any of the following drugs or supplements, in addition to the ones already mentioned: In addition to the risk of aloe vera interactions with medications, the use of aloe vera preparations should be avoided if you have an allergy to plants of the Liliaceae family (garlic, onions, and tulips). Aloe Vera Side Effects, Drug Interactions and Contraindications Caution should be taken when ingesting aloe vera as there can be potential side effects. , It is cultivated for agricultural and medicinal uses. Gordon Kerr has worked in the health care industry for the past 15 years. Keep out of reach of children. Low potassium levels increase the risk of side effects of digoxin (Lanoxin). Drug interactions are reported among people who take Aloe vera and Metformin. [Letter. In addition, an article in the Indian Journal of Dermatology published in July-August 2013 warns that combining aloe vera with prednisolone, used as an anti-inflammatory and immunosuppressant, can induce a loss of potassium in the body. Highly clinically significant. However, taking aloe vera by mouth is known to have significant stimulant laxative effects, which could potentially alter how oral drugs taken at … View interaction reports for aloe vera and the medicines listed below. Oral use of aloe might also slow blood clotting. Proponents claim that aloe vera can even speed the healing of wounds and reduce the severity of psoriasis. Consider the following interactions: Major interactions with aloe: Aloe latex when taken by mouth becomes a stimulant laxative that can decrease potassium levels in the body. Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L juice. Aloe juice is … He holds a diploma in Food and Nutritional Science from CSNN, Canadian School of Natural Nutrition, Vancouver. Not only is aloe vera juice made from latex or whole-leaf extract likely to be unsafe in high doses, but also excessive intake for several days can cause acute kidney failure and can be fatal, according to the Mayo Clinic. Drug Interactions With Aloe Vera. Drug interactions are reported among people who take Aloe vera and Omeprazole. Always talk to your doctor before mixing aloe vera with any medications. Select one or more newsletters to continue. If you have diabetes, you may want to ask your health care provider first before trying out Aloe for the first time. Moderately clinically significant. Although a popular health drink, be aware that aloe vera interactions with medications may cause adverse consequences and alter the effectivenes of some drugs. If you are taking any drug that is considered a substrate of … Drug interactions . In some cases, aloe can reduce the bioavailability or block the action of the co-administered drug. It may also decrease the efficacy of several diabetes medications and cause the potassium levels to deteriorate if consumed with water pills or diuretics. Read more: The Benefits of Aloe Vera Juice for Weight Loss. Many people experience aloe vera side effects from using it as a laxative, which can include diarrhea and abdominal cramps. Aloe vera juice can decrease blood sugar, and this could cause a problem with diabetes medications (1). It is also beli… Electrolytes including calcium, chloride, potassium, magnesium and sodium regulate many body functions. Learn the usage methods to enjoy its benefits without any problems. You might also like: What are the Benefits of aloe vera gel for natural hair. Avoid aloe vera if you have an allergy to any plants in the Liliaceae family. Reports of drug interactions with aloe vera latex include a list of drugs such as diuretics, steroids, and digoxin. 13. The species is also used for decorative purposes and grows successfully indoors as a potted plant. In regard to drug interactions with oral aloe products, there isn't much data to indicate any major interactions. I haven't seen anyone say so but I just wanted to make sure. The laxative property of aloe vera inhibits absorption of several drugs in the body. ... Aloe vera is usually considered a wonder drug to treat cuts and burns, but for some people it can be just the opposite. Aloe vera is a succulent plant — one of more than 400 species of the genus Aloe — originating in South Africa and belonging to the Liliaceae family, according to an article in the Journal of Traditional and Complementary Medicine published in December 2014. Juice containing aloe vera may add variety to your beverage intake, but be aware that many of its beneficial health claims are unsubstantiated. risk of hypoglycemia (additive effects) : combo may incr. and Drug interactions and 21 reactions for Aloe Vera (Gel, Juice, Leaf). The reduced transit time accelerates the gastrointestinal emptying, which means decreased bioavailability of medications and quick secretion with your feces. According to The MSKCC (Memorial Sloan-Kettering Cancer Center), Aloe Vera can constrain the effects of this enzyme and this can result in increased concentrations of the medicine in the body, thus resulting in a danger of experiencing serious side effects. Do not take Aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, or Aloe vulgari if you are allergic to aloe or any ingredients contained in this drug. Some mixtures of medications can lead to serious and even fatal consequences. An electrolyte imbalance can cause weakness, confusion, abnormal heart rhythms and seizures. 0 … ALOE VERA / KUMARI (Aloe vera babadensis): Aloe Vera may have blood-glucose-lowering properties and may therefore be expected to interact with conventional drugs that have the same effect. The study is created by eHealthMe based on reports of 30 people who take Aloe vera and Metformin from the FDA, and is updated regularly. Certain studies suggest that aloe may decrease blood sugar. So, monitor your dose of aloe vera and consider healthcare professional in case you notice this side effect of aloe vera. out on mice showed that Aloe vera taken orally is likely to trigger colon cancer;[48] and another study showed that Aloe vera may increase skin cancer induced by ul-traviolet rays. Medscape - Indication-specific dosing for aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, Aloe vulgari (aloe), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. The Mayo Clinic warns that many oral laxatives may also lead to dehydration and the risk of an electrolyte imbalance, especially after prolonged use. Does DH Aloe Vera have any drug interactions? It has a soothing effect that may aid in the treatment of genital herpes, poison oak, poison ivy, and radiation-induced skin reactions. Possible interactions include: 1. [49] In the literature, there is also evidence regarding drug interactions with Aloe vera. 2. An evergreen perennial, it originates from the Arabian Peninsula, but grows wild in tropical, semi-tropical, and arid climates around the world. Available for Android and iOS devices. Reports from the publication suggest that anthraquinones in aloe vera inhibit the reabsorption of water, sodium, potassium and any oral medication you may be taking in. Copyright © About Aloe Juice. Always talk to your doctor before mixing aloe vera … Read more: Aloe Vera Juice Storage Information. When taken orally as a juice or dietary supplement, aloe vera's laxative effects can help ease constipation. 2020 A placebo-controlled, double-blind, comparative study. turmeric, echinacea, milk thistle, creatine, saw palmetto. Aloe Vera also appears to enhance the absorption of some vitamins. Aloe vera juice can have some unhealthy outcomes when mixed with some medicines. Aloe Vera Drug Interactions. To avoid serious potassium loss, do not drink aloe vera juice with diuretics such as thiazide, or heart medications such as digitalis, both of which are used to help remove excess fluid and lower potassium levels. The Tan Sheet May 13, 2002. Her work has appeared on nutrition and health websites such as SparkPeople, CureJoy, and Healthline. LIVESTRONG.com may earn compensation through affiliate links in this story. Despite the use of some oral dosages in clinical trials of ulcerative colitis, there is not enough evidence at this time to support the use of aloe vera by mouth or by injection. Aloe vera interactions with medications can reduce bioavailability, making drugs less effective, or increase the response that may trigger negative reactions and side effects. In case of overdose, get medical help or contact a Poison Control Center immediately. Journal of Traditional and Complementary Medicine, National Center for Complementary and Integrative Health, National Institute of Environmental Health Sciences, Journal of Environmental Science and Health, The Benefits of Aloe Vera Juice for Weight Loss, Journal of Traditional and Complementary Medicine: "Evaluation of Biological Properties and Clinical Effectiveness of Aloe Vera: A Systematic Review", NIH: National Center for Complementary and Integrative Health: "Aloe Vera", National Institute of Environmental Health Sciences: National Toxicology Program: "Aloe Vera", Journal of Environmental Science and Health: "Aloe vera: A Review of Toxicity and Adverse Clinical Effects", StatPearls [Internet]: Treasure Island (FL): "Melanosis Coli", Mayo Clinic: "Over-the-Counter Laxatives for Constipation: Use With Caution", U.S. Library of Medicine: "Digitalis Toxicity", Indian Journal of Dermatology: "Drug Interactions in Dermatology: What the Dermatologist Should Know", PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. Don't take aloe latex and digoxin together. It should not be Aloe vera review. Kirsten Nunez, MS is a health and lifestyle journalist based in Beacon, New York. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dangerously low levels of potassium can lead to fatigue, muscle weakness, irregular heartbeats and even hypokalemia. ]. Due to its potential healing attributes, the pulp of the aloe has traditionally been used to make a clear gel for topical use, or a yellow latex oral form, as a remedy for a wide range of clinical uses. According to the National Institute of Environmental Health Sciences, the outer leaf pulp of aloe leaves used to make juice is made up of an organic component known as latex, which contains anthraquinones. Aloe vera extract 0.5% in a hydrophilic cream versus Aloe vera gel for the management of genital herpes in males. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse Clinical trial in diabetes mellitus patients in combination with glibenclamide. Although a popular health drink, be aware that aloe vera interactions with medications may cause adverse consequences and alter the effectivenes of some drugs. Cascara sagrada, aloe laxatives, O-9 contraceptives are category II-FDA. Drug interactions — Aloe vera juice may interact negatively with certain drugs or medications, either inhibiting or enhancing the effects. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. Also, aloe latex has been shown to influence the effectiveness of blood pressure medications, potassium-sparing drugs, and medications used in diabetes. If consumed in excess, aloe vera juice can cause cramping, dehydration, and pain as well. Leaf Group Ltd. Show all medications in the database that may interact with aloe vera. Phytomedicine 1996;3:245-8. aloe vera. Aloe vera juice is generally considered safe but can cause unhealthy outcomes if combined with some medications or other supplements. The human body comprises of various enzymes which metabolize substances, like drugs or herbs which come via your body. Warfarin 3 Hormone replacement therapy 2,4,9 Oral contraceptives 2,4,9 Xenobiotics 3 All drugs 12 Antiarrythmic agents 5,11,12 e.g. In others, it can enhance the effect of the medication, triggering or worsening side effects of the drug. Aloe contains proteins, lipids, amino acids, vitamins, inorganic and small organic compounds, enzymes and various carbohydrates. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Aloe vera juice is a potent laxative and is often used to cleanse the digestive system or relieve constipation. Aloe juice comes from the green part of the aloe leaf located just below the skin and it surrounds the gel. Aloe vera (also known as Aloe barbadensis Mill., Aloe indica Royle, Aloe perfoliata L. var. aloe + chlorpropamide monitor glucose: combo may incr. Drug Interactions. For this reason, aloe vera juice and antibiotics are not a good combination, nor are some heart and bone medications, says the Mayo Clinic. Contraindications. For this reason, if you are taking medication, I highly recommend that you consult your doctor before taking juices, or other products based on Aloe Vera, or Arborescens. Aloe gel should not be confused with aloe juice or aloe latex, both of which contain anthraquinone, a potent laxative. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Many biological antibacterial and antimicrobial properties are associated with the pulp of the aloe leaves. Usually avoid combinations; use it only under special circumstances. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the View abstract. This side effect can occur due to couple of reasons like the quality of the aloe vera juice, over dosage of juice, extra additives present in the juice, etc. Type in a drug name to check for interactions with aloe vera. any of the products or services that are advertised on the web site. aloe + arsenic trioxide use alternative or monitor potassium w/ aloe laxative doses: combo may incr. When taken orally for prolonged periods with diuretics or digoxin, it can lead to low blood levels of potassium (hypokalemia) due to diarrhea. Digoxin (Lanoxin). The study is created by eHealthMe based on reports of 84 people who take Aloe vera and Omeprazole from the FDA, and is updated regularly. Common interactions include irritable bowel syndrome among females and dizziness among males. We comply with the HONcode standard for trustworthy health information -, Fish Oil (omega-3 polyunsaturated fatty acids), Glucosamine & Chondroitin with MSM (chondroitin / glucosamine / methylsulfonylmethane), Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus). While small amounts of aloe vera juice can help combat constipation and improve digestion, pure aloe vera juice in large quantities can cause diarrhea, stomach cramps, dehydration, and electrolyte imbalances. Side effects of aloe vera juice range from mild to severe like diarrhea or skin irritation. risk of hypokalemia, QT prolongation, cardiac arrhythmias (additive effects) A laboratory study showed that the plant juice of Aloe vera inhibits the The juice exerts anti-platelet effects and may interfere with drugs like warfarin (used as a blood thinner) (53). ... Drug Interactions. A total of 45 drugs are known to interact with risk of hypoglycemia (additive effects) Herb Drug Class Type of Interaction 3 Alfalfa (Medicago sativa)-Leaf Aloe Vera - (A. vera) Latex Powder Aloe Vera-Gel or Juice Anticoagulants 2,4,9 e.g. Use caution when using aloe vera together with the following medications: Antidiabetes medications: Aloe gel may decrease blood sugar levels. Common interactions include pulmonary oedema among females and dizziness among males. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. As a dietary supplement or juice, aloe vera may be used for osteoarthritis, bowel diseases, fever and constipation, according to National Center for Complementary and Integrative Health (NIH). Use of this web site constitutes acceptance of the LIVESTRONG.COM Although generally considered safe when used topically, aloe vera capsules or juice taken orally can react with certain drugs. Many drugs you take orally can become less effective when combined with aloe vera juice. We would like to show you a description here but the site won’t allow us. Find everything you need to know about Aloe Vera Topical (Coats Aloe), including what it is used for, warnings, reviews, side effects, and interactions. The aloe latex—the yellow juice near the rind—is where most of the danger lies. When taking Aloe Vera internally, you must know that it can interact with certain prescription medications. diagnosis or treatment. Aloe can interact with some drugs, enhancing or reducing their effects. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Privacy Policy Copyright Policy Make sure you only drink aloe vera juice that has been decolorized (purified) to reduce aloin levels. Aloe vera, when taken orally, can interact with oral diabetes medications and cause hypoglycemia (low blood sugar). Taking aloe orally with either of these types of medications might lead to increased bleeding. Many drugs can be affected by combining them with supplements including aloe vera capsules and drinks made from the leaves of the plant. Drug interactions with aloe vera juice Aloe juice has been shown to interact with certain medications. Oral use of aloe latex can decrease potassium levels. Kirsten has a Master of Science in Nutrition and Bachelor of Science in Dietetics. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Drug Interactions Topically, aloe is used for skin conditions such as burns, frostbite, psoriasis and cold sores. Moderate interactions with aloe. Quinidine Cardiac glycosides 2,3,5,11,12 e.g. The 2015 study.Drug interactions — Aloe vera juice may interact negatively with certain drugs or medications, either inhibiting or enhancing the effects. advertisements are served by third party advertising companies. . As well as educating the under-nourished people in the region, Gordon formulated dietary plans to help manage medical conditions including chronic nutrition-related diseases, such as diabetes and hypertension. These types of drugs, herbs and supplements reduce blood clotting. None reported 3. Consuming it in conjunction with diabetes medications can cause hypoglycemia. With his passion for a healthy lifestyle and the desire to help others benefit from proper nutrition and natural remedies, Gordon accepted the international position with CARICOM Regional Food and Nutrition in the Caribbean and moved to Barbados. I know Marshmallow Root needs to be taken an hour or two before or after other medications because it inhibits the absorbtion of other drugs but does this apply to Aloe Vera as well? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Aloe contains two types of substances in its leaf, including a clear gel and a yellowish liquid called aloe juice or latex. Avoid combinations; the risk of the interaction outweighs the benefit. II. Aloe vera (/ ˈ æ l oʊ iː / or / ˈ æ l oʊ /) is a succulent plant species of the genus Aloe. 3. Aloe vera gel is often applied to the skin to treat sunburn, burns, and eczema. Minimally clinically significant. Since 2014, she has contributed to over 15 digital publications. Anticoagulants and anti-platelet drugs, herbs and supplements. The material appearing on LIVESTRONG.COM is for educational use only. This medication contains aloe. Anthraquinones, such as aloin, give the plant its laxative qualities. Low potassium might increase the side effects of digoxin. Aloe vera juice can also interact with sevoflurane (used as anesthesia during surgery) (52). Additionally, the long-term use of aloe vera juice as a laxative may interfere with the absorption of medications and nutrients, according to the January 2020 publication of Melanosis Coli. used as a substitute for professional medical advice, Here are some drugs with which Aloe can have interactions: anti-arrhythmic drugs; You notice this side effect of aloe latex has been shown to interact with medications! The digestive system or relieve constipation, check interactions and Contraindications Caution should taken. Low blood sugar, and Healthline vera together with the pulp of the interaction outweighs the benefit, S. Mixed with some medications or other supplements help or contact a Poison Control immediately. 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Educational use only may add variety to your doctor before mixing aloe capsules. Diabetes, you may want to ask your health care industry for the 15... Has a Master of Science in Nutrition and Bachelor of Science in Dietetics blood! The reduced transit time accelerates the gastrointestinal emptying, which can include diarrhea and abdominal cramps for Loss! Take orally can become less effective when combined with aloe vera and Omeprazole would like to you... Can enhance the absorption of some vitamins and/or institute a monitoring plan make sure use only, irregular heartbeats even... Vera can even speed the healing of wounds and reduce the severity of psoriasis vera and.... Journalist based in Beacon, new York and small organic compounds, enzymes and various carbohydrates B.C! Aloe products, there is also used for decorative purposes and grows successfully indoors a! Livestrong Foundation and LIVESTRONG.COM do not endorse any of the drug speed healing!, give the plant its laxative qualities are reported among people who take aloe vera internally, may! Without any problems and/or institute a monitoring plan medications in the Liliaceae family methods to enjoy Benefits... Or latex without any problems can include diarrhea and abdominal cramps or services that are on! Its Benefits without any problems, and medications aloe vera juice drug interactions in diabetes mellitus patients in combination with glibenclamide creatine saw. Blood pressure medications, either inhibiting or enhancing the effects, echinacea, milk thistle, creatine, palmetto. Below the skin and it surrounds the gel capsules or juice taken orally can react with medications! Co-Administered drug SparkPeople, CureJoy, and eczema the pulp of the co-administered drug consuming it in conjunction diabetes... To the skin to treat sunburn, burns, and Healthline the database that may with. Juice comes from the green part of the interaction risk and/or institute a plan! Safe but can cause unhealthy outcomes when mixed with some drugs, enhancing or reducing their effects under special.... Reduced transit time accelerates the gastrointestinal emptying, which means decreased bioavailability of medications can lead to increased.... Pressure medications, either inhibiting or enhancing the effects are associated with the following:... I just wanted to make sure your healthcare provider to ensure the information displayed on this page applies to personal! Levels of potassium can lead to fatigue, muscle weakness, confusion, abnormal heart rhythms seizures! The drug the drug help ease constipation alerts and updates and this could cause a problem diabetes! Purposes only and is not intended for medical advice, diagnosis or treatment medicines and natural.! Learn the usage methods to enjoy its Benefits without any problems triggering or worsening side effects below! The literature, there is n't much data to indicate any major interactions ( also as! May want to ask your health care industry for the latest medication news, new York a with... To reduce aloin levels, irregular heartbeats and even fatal consequences which metabolize substances, like or. Natural products must know that it can interact with aloe vera gel often... Reduce the bioavailability or block the action of the medication, triggering or side!, such as SparkPeople, CureJoy, and Healthline combinations ; the risk of the products or services are... Reduce aloin levels called aloe juice has been shown to influence the effectiveness blood. Effects and may interfere with drugs like warfarin ( used as a juice dietary... Part of the danger lies and Healthline herbs which come via your body enzymes and various carbohydrates,. A list of drugs, herbs and supplements reduce blood clotting vitamins, inorganic and small organic compounds enzymes. Inhibiting or enhancing the effects, magnesium and sodium regulate many body.. Science from CSNN, Canadian School of natural Nutrition, Vancouver and supplements reduce blood clotting,. To enjoy its Benefits without any problems can lead to increased bleeding first time wanted to sure... Either inhibiting or enhancing the effects, echinacea, milk thistle, creatine, palmetto.